San Mateo Science Center is a two-building, 259,000-square-foot campus in San Mateo, positioned at 901 and 951 Mariners Island Boulevard. As part of the broader San Mateo/Foster City life-science cluster—home to organizations such as Gilead Sciences and Illumina—the campus sits at the geographic center of the Bay Area, offering immediate connectivity to San Francisco, Silicon Valley, and the East Bay via Highways 101 and 92.

Beyond its Class A life-science, creative technology, and office environments, the campus delivers a refined amenity experience programmed by Elevate, Longfellow’s proprietary tenant concierge program. The Commons offers an elevated mix of spaces, including an upscale meeting and coworking lounge, a coffee bar and café, flexible training and conference rooms, a fitness center with showers and lockers, and an outdoor patio complete with fire pit and heaters—creating a seamless blend of productivity, wellness, and community.